Researchers announce that dog longevity drug may be effective for humans too

By SecretWuff 4 Min Read

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Last year, a biotech company called Royal revealed they were working on a drug that could extend the lifespan of our four-legged best friends, and today they plan to launch it early this year.

Royal says it is confident that its anti-aging drug LOY-002 will be launched this year.

LOY-002, one of Biotechnology’s anti-aging drugs, is a daily beef-flavored tablet specially developed for dogs over 10 years of age and weighing over 14 pounds.

“We are developing LOY-002 to support healthy aging in senior dogs of almost any size.” royal reveals their Website. “This product aims to target metabolic dysfunction, which may extend your dog’s healthy lifespan and support their quality of life into old age.”

guardian Royal reported that it had raised $125 million in funding from companies that had refrained from investing in human longevity projects because testing would take decades.

But Royal founder and CEO Celine Harioua believes their work on anti-aging drugs for dogs could one day benefit humans as well.

“Finding a way to prevent age-related decline in dogs is a very powerful proxy for doing the same thing in humans, because dogs suffer from similar age-related diseases and experiment Because they share their environment and habits with us in a different way. she said.

Halioua said they are not creating immortal dogs. In fact, dogs are living longer “By extending healthy lifespan and reducing the rate of aging.”

Middle-aged man hugging his dog during a walk
Kazantseva Olga / Shutterstock.com

Similarly, dog aging project They are studying at the University of Washington that low doses of rapamycin can slow the aging process in dogs.

Rapamycin is a cheap and easily produced drug that is already commonly used as an immunosuppressant after organ transplant surgery in humans.

Researchers believe that regulating cell growth and metabolism could improve both cardiac and cognitive function in dogs, extending their lives.

Daniel Promislaw, a biological gerontologist at the University of Washington and co-director of the Canine Aging Project, said: “Our research is light years ahead of anything that has ever been done or can be done on humans. What we are doing is That’s 40 years of human research testing the drug’s ability to extend lifespan.”

Although the drug has not been officially approved for use in human longevity, gerontologists believe it may have future potential.

The project’s co-founder and lead veterinarian, Kate Creevy, also told the Guardian that research on spayed and unneutered dogs could provide insight into the health of women around menopause. spoke.

Creasy explains: “We also have data on what age dogs were spayed, which can influence variations in the age of menopause in women. We also have data on why dogs were spayed. It may also affect women who have had a hysterectomy for medical reasons.”

Additionally, Promislow expects that when the project is finally reported in four to five years, rapamycin will have the ability to keep dogs healthy for three more years of their lives.

Promislaw said: “If we can successfully treat dogs, this could be a turning point in our understanding of how to extend healthy lifespans in humans.”

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